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المملكة العربية السعودية - العربية مصر - العربية
IHC experiments to detect PEG were conducted to further examine the relationship between the administration of Jintrolong® and the development of vacuolation rein the CP. As shown hinein Figure 4, no PEG staining was detected hinein the brain CP in animals of the control group (Figures 4A–C) or the 0.3 Magnesium/kg group (Figures 4D–F). However, positive anti-PEG welches observed rein animals at 1 Magnesium/kg (Figure 4G) and with an even stronger staining signal at 3 mg/kg (Figure 4J).
Despite the intensive research on cytotoxic induction of vacuolation and its downstream effects, there is no definitive mechanism or functional impact of vacuolation (15, 16). Theoretically, significant cellular vacuolation could result rein the disruption of the cytoarchitecture, leading to compromised function of tissues, such as epithelial cells rein the CP.
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No formal hypothesis testing welches performed. All AEs were coded using MedDRA. All TEAEs were summarized and presented in the listings by the number of subjects reporting an Veranstaltung, the percentage of subjects with that Fest, the number of events, the eben, and the relationship to treatment. Percentages were calculated based on the number of subjects who received the treatment during the study.
Reduction of excessive amounts of fat hinein weed online kaufen the body (especially abdominal fat). Reduction of abdominal fat is the strongest and most visible effect of Jintropin.
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Since vacuolation did not obviously affect the subcellular structure or cell proliferation of CP epithelial cells, the next question is whether the vacuolation in CP affected the function of CP epithelial cells and the brain. The indices of CP function measured were secreted CSF and cell metabolism of glucose.
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Whole-brain slides were checked. Positive PEG staining welches only detected in CP and blood vessels (Figure 4G) but not rein other brain tissues, indicating that PEG or Jintrolong® welches unlikely to cross the blood-brain barrier composed of CP cells and enter other brain tissue.
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